It really is now clear from a number of studies that getting treatment as quickly as possible after aids thai is superior to waiting. HIV-infected patients that are treated early have fewer complications from HIV infection and are unlikely to infect other people compared to those who wait to be treated. Studies also demonstrate that people that know they may be HIV-positive may change their behavior to diminish the risk of infecting others.
Globally, approximately 45% of men and women coping with HIV know about their HIV status, far beneath the 90% target set out recently by WHO and UNAIDS. The greatest quantities of people experiencing undiagnosed HIV will be in sub-Saharan Africa, where fragile health and laboratory systems have hindered efforts to scale up HIV testing coverage. In low-income, high HIV burden countries with limited technological infrastructure, rapid diagnostic tests (RDTs) are popular in diagnostic algorithms.
RDT accuracy could be undermined by poor operator practice , and also by storage at ambient temperatures above manufacturer guidelines . Poor accuracy of RDTs and subsequent misclassification can result in a) if falsely diagnosed HIV-positive, unnecessary worry and initiation on antiretroviral therapy; or b) if falsely diagnosed HIV-negative, missed opportunities for linkage to HIV care and prevention services
The scale-up of HIV self-testing (HIVST) using oral fluid testing will pose additional challenges to maintaining accuracy in HIV testing programmes. Self-testing is based on an individual performing and interpreting their own personal HIV test result. Oral fluid RDTs designed for self-testing could be held in uncontrolled settings (e.g. people’s houses) 57dexlpky prolonged periods before use and they are less amenable to formal quality assurance (QA) programmes . We therefore lay out to evaluate two facets of RDT kit stability: the impact of prolonged field exposure to high temperature on the accuracy of whole blood and oral fluid RDTs; as well as the stability of oral RDT results with delayed visual re-reading.
In October 2004, conventional HIV testing was changed when OraSure Technologies, Inc., announced that it had U.S. FDA approval for the rapid HIV test that could detect antibodies to both HIV-1 and HIV type 2 (HIV-2). This is called the OraQuick Advance Rapid HIV-1/2 Antibody Test. It absolutely was the first available test that may provide results in 20 mins using oral fluid, a finger-stick sample of blood, or plasma. Rapid HIV tests are now recommended and is one of the mainstay of many HIV screening programs.